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Premenstrual syndrome (PMS)

A brain-based perspective

Monthly mood and body shifts

PMS (premenstrual syndrome) involves physical and emotional symptoms that emerge in the luteal phase of the menstrual cycle. These can include mood changes, irritability, bloating, fatigue, and breast tenderness, and usually resolve when menstruation begins. For some, these symptoms are manageable but for others, they affect daily functioning and quality of life.

Widespread, but often overlooked

An estimated 75% of women and people with periods experience some form of PMS. While milder than PMDD, PMS still has real physical and psychological effects. Because the symptoms are common and occur every month, they’re frequently minimized despite their impact.

Treatment options

Care for PMS includes lifestyle adjustments, diet, and medication - but newer approaches are expanding what’s possible. Brain-based tools that target mood management and how the body responds to pain are being used to help hormonal shifts. By working with the brain-body connection, it's a more personalized way to find relief.

Be in control of your PMS experience

Track your symptoms and spot patterns to manage mood, focus, and energy throughout your cycle.

Keep track in your own words

Discover patterns in your experiences

Integrate your data and your care plan

See your progress over time

Support for your cycle, even at its most challenging phase.

Struggling with brain fog, low mood, and PMS before your period?

Nettle™ is a brain-based wearable that eases menstrual pain and mood, making you feel clearer, calmer, and more focused.

Nettle™ is a certified medical device, clinically proven to reduce menstrual pain.

It also helps support focus and emotional regulation in the lead-up to your period.

Your Nettle™ purchase includes a Samphire membership, including tools to track, learn and get support through every phase of your cycle.

Neurodiverse users are already experiencing improvements.

Our solutions are informed by neuroscience. These are the experiences of people using them every day. Read all reviews

The device is worth every cent.
Silvija
I've actually found my pain levels have reduced since using this device!
Alison
The changes have been remarkable. My mood and motivation have improved significantly, and I’ve experienced zero menstrual pain! It’s been a total game-changer!
Steph
Remarkable Improvement in My PMS and Menstrual Pain. In the first month, I didn’t notice much of a difference. But in the second month, my PMS symptoms were reduced by 50%. Then in the third month, my PMS symptoms were reduced by 80%!
Moko Chan
94%

Feel better in just three months.

Our mission is to empower women to take ownership of their cycle.

Explore other brain-based perspectives

When it comes to healthcare, the brain is the missing link.