
Premenstrual syndrome (PMS)
A brain-based perspective
Monthly mood and body shifts
PMS (premenstrual syndrome) involves physical and emotional symptoms that emerge in the luteal phase of the menstrual cycle. These can include mood changes, irritability, bloating, fatigue, and breast tenderness, and usually resolve when menstruation begins. For some, these symptoms are manageable but for others, they affect daily functioning and quality of life.
Widespread, but often overlooked
An estimated 75% of women and people with periods experience some form of PMS. While milder than PMDD, PMS still has real physical and psychological effects. Because the symptoms are common and occur every month, they’re frequently minimized despite their impact.
Treatment options
Care for PMS includes lifestyle adjustments, diet, and medication - but newer approaches are expanding what’s possible. Brain-based tools that target mood management and how the body responds to pain are being used to help hormonal shifts. By working with the brain-body connection, it's a more personalized way to find relief.
Be in control of your PMS experience
Track your symptoms and spot patterns to manage mood, focus, and energy throughout your cycle.
Support for your cycle, even at its most challenging phase.
Struggling with brain fog, low mood, and PMS before your period?
Nettle™ is a brain-based wearable that eases menstrual pain and mood, making you feel clearer, calmer, and more focused.
Nettle™ is a certified medical device, clinically proven to reduce menstrual pain.
It also helps support focus and emotional regulation in the lead-up to your period.
Your Nettle™ purchase includes a Samphire membership, including tools to track, learn and get support through every phase of your cycle.

Neurodiverse users are already experiencing improvements.
Our solutions are informed by neuroscience. These are the experiences of people using them every day. Read all reviews

Feel better in just three months.
Our mission is to empower women to take ownership of their cycle.
Our mission is to empower women to take ownership of their cycle
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