
Dysmenorrhea
A brain-based perspective
Painful periods
Dysmenorrhea refers to cramping and pain before or during menstruation. For some, it’s mild and short-lived. For others, the pain can be severe, radiating through the lower back and thighs, and accompanied by nausea, fatigue, or even fainting. It’s one of the most common reasons people miss school, work, or everyday activities.
Common and often minimized
Up to 80% of women and people with periods experience dysmenorrhea at some point, yet it’s often dismissed as “normal.” Severe or recurring pain can signal underlying issues like endometriosis or fibroids, but many go without evaluation or support. Because period pain is so common, it’s easy to overlook when it crosses the line into something more serious.
Hormone aware care
Treatments include anti-inflammatory medications (like NSAIDs), hormonal contraceptives, heat therapy, and exercise. When standard options fall short, newer approaches like nervous system regulation and brain-based pain care, can offer relief by addressing how pain is processed and amplified. Understanding dysmenorrhea as both a physical and neurological experience opens doors to more effective care.
Gain a better understanding of your period pain
Understand the role that period pain plays on your brain across your cycle, and gain the tools and insight you need to feel in control.
Support for your period pain and beyond.
Struggling with cramps, fatigue, or PMS symptoms?
Nettle™ is a brain-based wearable approved for menstrual pain and mood, that helps users feel more able to function and manage pain symptoms.
Nettle™ is a certified medical device, clinically proven to reduce menstrual pain.
It also helps support focus and emotional regulation in the lead-up to your period.
Your Nettle™ purchase includes a Samphire membership, including tools to track, learn and get support through every phase of your cycle.

Women around the world are already experiencing improvements.
Our solutions are informed by neuroscience. These are the experiences of people using them every day. Read all reviews

Feel better in just three months.
Our mission is to empower women to take ownership of their cycle.
Our mission is to empower women to take ownership of their cycle
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When it comes to healthcare, the brain is the missing link.