Samphire device on bench
Samphire device on bedside table
Samphire device on white background
Woman wearing Nettle device
Woman wearing Nettle device
Woman wearing Nettle device

Studied, designed and supported by teams from

Nettle™

Medical Wearable for Menstrual Pain and Mood Relief

Nettle™ is not available in US

You're browsing our US store, where Nettle™ is not available. Discover Lutea™, based on the same award-winning technology, and available in your region.

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1 Year Warranty
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See what our users are saying

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Why the brain

89% of our users report using fewer medications

All statistics taken from the Six Month Nettle User Survey (2025)

0%

of users report "fewer sick days or interruptions to daily life"*

0.0

fewer GP or specialist visits reported on average per user per year

0%

of all users reduced their use of hormonal treatments.

A daily routine for people just like you.

Rated Excellent on Trustpilot.

Illustration of personalised cycle-based scheduling in the Samphire app
1

It's not random. It's a rhythm.

Even if its complex or irregular, your cycle has a pattern you can work with, not just endure. Build a Nettle™ schedule that is flexible enough for real life yet precise enough to support you when it matters most.

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Samphire

Session scheduled

21 min ago

Tap to start.

Samphire

Great progress

11 min ago

You're halfway through your session.

Samphire

Session complete

Now

Log how you feel to improve your schedule.

1

Be notified when you need it

Track your experiences in the Samphire app, and be notified when Nettle™ needs to be used.

1

Run sessions

Setup takes under a minute, and sessions run for twenty minutes.

Person comfortably going about daily activities while using Nettle
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Live life

Once your session starts, you are free to carry on—rest, work, or move through your day as usual. Nettle™ works quietly in the background, supporting you throughout your cycle.

Cycle insights and long-term progress view in the Samphire app
1

Monitor and adjust over time

Track patterns across cycles and learn what works best for your body. Support your cycle with confidence with Lutea™

Everything you need

Nettle™ comes with everything you need for stress-free stimulation.

Nettle™ Travel Case
Nettle™ Travel Case

Protect your Nettle™ when you're on the go.

Samphire Loop
Samphire Loop

For a tighter, snugger fit on the head.

$12.99 Included

Charger (EU / UK / US)
Charger (EU / UK / US)

Be ready to stimulate when you need it.

$14.99 Included

Solution Bottle
Solution Bottle

Store your solution in a convenient, leak-proof container.

$12.99 Included

Stimulation Refills
Stimulation Refills

30 sessions worth of sponges and salts.

$12.99 Included

What's in the box

Why the brain

Clinically tested for real-life support.

Nettle™ uses neuroscience, clinically tested technology and thoughtful design to create tools that help you feel more in control - improving focus, easing burnout, supporting mood and reducing brain fog.

Pink brain visualization

It’s all in your brain.

Mood, pain, motivation - they start and end in the brain.

Abstract golden flowing pattern

It’s not random. It’s a rhythm.

Even if its complex or irregular, your cycle has a pattern you can work with, not just endure.

Woman wearing neuroscience headband device

Clinically tested real-life support.

Nettle™ neuroscience and smart design to help you feel clearer, steadier, and in control.

Brain, body, mind – all working together.

Decades of research show that the brain can rewire itself - with the right kind of stimulation. Pair Nettle™’s cutting edge science with holistic care in the Samphire app. Working with your cycle, not against it, you build a foundation for relief.

nettle-mood-swings
Mood Swings

Mood Swings

Nettle™ rebalances activity in the brain’s prefrontal cortex, helping calm fight-or-flight responses.

Integrated care

Integrated care

Nettle™ integrates with Samphire, giving you personalised guidance across your entire cycle.

Pain Relief

Pain Relief

Nettle™ retrains the brain’s response to pain by modulating overactive pathways - teaching your system to react differently.

Cycle resilience

Cycle resilience

Each time you use Nettle™, you’re creating adaptive brain responses to boost your overall reslience.

94% of users feel better in just three months.*

We invest in rigorous science, conducting randomized, placebo-controlled, double-blind clinical trials to ensure the safety and effectiveness of Nettle's™ technology.

Harvard University
UFRN
Queen Mary University of London
NHS

97%

of users find Nettle™ easy to integrate into their lives.

[2024 Nettle Usability Study]

67%

noticed mood improvements within one cycle.

[2024 WIND Clincal Trial]

72%

experienced reduced pain within one cycle.

[2024 WIND Clincal Trial]

93%

felt relief within three cycles of personalized use.

[2025 Nettle User Survey]

What we help with

Explore our perspectives on women’s health below.

Too often, systems treat symptoms in isolation. Samphire’s solutions work across the brain, body and cycle - connecting the dots between pain, mood, focus, hormones and more.

Endometriosis

Endometriosis

Highly prevalent chronic inflammation.

Premenstrual syndrome

Premenstrual Syndrome

Widespread but often overlooked mood and body shifts.

showing brain with gears

ADHD and Neurodiversity

Differences in focus and attention.

Neuroplasticity

Neuroplasticity

The brain's ability to reorganize and adapt through experience.

pmdd

Premenstrual Dysphoric Disorder

Severe PMS symptoms causing mood changes and physical discomfort.

Dysmenorrhea

Dysmenorrhea

Painful menstrual cramps that can disrupt daily activities.

Sleep and rest

Sleep and Rest

Supporting quality sleep to restore energy and balance.

Emotions and mood swings

Emotions and Mood Swings

Managing sudden mood shifts and emotional sensitivity.

Stress and anxiety

Stress and Anxiety

Reducing tension and calming the mind during the cycle.

Our Blogs

Learn about the cycle brain connection