As Research Lead at Samphire, you’ll be foundational in shaping the scientific future of women’s brain health. You’ll define and drive our long-term scientific activities, guiding the company’s research strategy from preclinical discovery through to clinical validation and therapeutic impact.

You’ll join our small, mission-driven team at a pivotal time in our growth. Reporting to the CEO, you’ll lead and expand our research function, working in close partnership with our clinical, product, and regulatory teams to ensure our technology remains scientifically rigorous, clinically meaningful, and deeply patient-centered.

This is a multidisciplinary leadership role suited for someone with a deep background in neuroscience or neurotechnology, a passion for translational research, and a desire to shape the scientific foundation of a category-defining company in women’s health.

What You’ll Do

Scientific Strategy

Define and lead the long-term scientific roadmap for Samphire. Align preclinical research, clinical goals, and innovation priorities across a multi-year horizon.

Pipeline Development

Expand Samphire’s scientific pipeline, identifying new indications and target populations based on strong mechanistic rationale and unmet need.

Research Oversight

Guide all scientific programs, including protocol development, preclinical model design, and collaboration with academic and CRO partners. Ensure a high bar for scientific rigor across all studies.

Clinical Translation

Bridge preclinical research and clinical development. Collaborate with clinical and regulatory leads to ensure our trials are grounded in evidence and positioned for success.

External Leadership

Build and nurture relationships with key opinion leaders, advisors, grant agencies, and scientific partners. Represent Samphire’s scientific vision in public forums, publications, and advisory settings.

Team Building

Recruit and lead a world-class scientific team. Foster a culture of curiosity, integrity, and collaboration across all research functions.

Cross-Functional Collaboration

Partner closely with product, regulatory, marketing, and executive teams to ensure scientific insights are embedded across the company. Help shape patient narratives, clinical positioning, and commercialization through science-first thinking.

What We’re Looking For

• PhD or MD/PhD in neuroscience, neuroengineering, biomedical sciences, or a related field.
• 5+ years of experience leading translational research, ideally across both preclinical and clinical domains.
• Expertise in neurostimulation, neuromodulation, or adjacent fields
• Familiarity with regulatory pathways like 510(k) or De Novo.
• Track record of leading research programs (including in a university setting) from concept to clinical stage.
• Clear communication with technical and non-technical audiences alike.
• Motivated by mission, impact, and advancing the science that underpins real-world outcomes.

Nice-to-haves

• Experience working with noninvasive or invasive neuromodulation, neuroimaging, and/or closed-loop neurotech.
• Track record of publications in top-tier journals.
• Familiarity with women’s health, pain, or psychiatric research.
• Experience leading cross-functional teams or working in a startup or early-stage biotech environment.
• A strong network of collaborators and research partners.
• Deep commitment to scientific integrity and patient outcomes.

Why Join Samphire?

• We're redefining how women manage chronic pain through noninvasive neurotechnology—starting with tDCS for PMDD and endometriosis.
• Join at a defining moment and help build the scientific engine behind the next generation of personalized neurotherapeutics.
• You’ll lead programs that translate into clinical access and real-world impact.
• You’ll have the autonomy to shape direction, mentor talent, and establish a legacy of rigorous, human-centered science.
• We’re a remote-first team with presence in London, San Francisco, New York, and Boston. We offer fully equipped office space in Central London.

How to apply

Send your application with subject line 'CSO Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV/resume/Linkedin.
• Your list of academic publications (if applicable).
• Example piece of published work.

Our selection process includes scientific and culture interviews with team members and advisors. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.

As Commercial / Market Access Lead at Samphire, you’ll be foundational in shaping how we bring the future of women’s neurohealth to market. You’ll define the company’s go-to-market playbook—across pricing, reimbursement, channel development, and partnerships—to ensure our life-changing technology is accessible, affordable, and widely adopted.

You’ll join our small, high-caliber team during an inflection point: we’re moving from clinical validation to commercial readiness. Reporting to the CEO, you’ll lead our efforts to scale with intention—crafting a business model that supports both growth and impact. You’ll work cross-functionally with product, marketing, clinical, and regulatory leaders to translate science into strategy, and strategy into sustainable revenue.

This is a builder role for someone excited by whitespace and complexity. You’ll lay the commercial foundation for a category-defining company in women’s health.

What You’ll Do

Commercial Strategy

Develop and lead Samphire’s multi-year commercial strategy—from launch through scale. Define how we monetize, where we focus, and how we reach patients and partners.

Pricing and Reimbursement

Own our pricing model and payer engagement strategy. Evaluate self-pay, hybrid, and reimbursed pathways across markets. Lead work on cost-effectiveness, value-based care positioning, and payer partnerships.

Channel Development

Design and test go-to-market models across DTC, B2B2C (clinics and providers), and payer-supported offerings. Build repeatable channels that reflect how women actually seek care.

Market Access

Lead the development of market access materials including economic modeling, outcomes data positioning, and stakeholder messaging for payers, clinicians, and employer groups.

Growth Infrastructure

Build the commercial systems we need to scale—across CRM, sales ops, forecasting, and performance tracking. Prepare Samphire to move from zero to one, and then from one to many.

Cross-Functional Leadership

Partner with product, regulatory, clinical, and marketing teams to ensure commercial strategy is grounded in patient insight, clinical evidence, and operational feasibility.

Team Building

Hire and manage high-performing talent across GTM, sales, and partnerships as the commercial function grows.

What We’re Looking For

• 8+ years of experience in commercial strategy, go-to-market, or market access roles—ideally in healthtech, medtech, or biopharma.
• You’ve led pricing and reimbursement strategies for novel healthcare products.
• You’ve built and executed on commercial models from scratch, and understand how to balance experimentation with execution.
• You have experience working across both direct-to-consumer and B2B2C business models.
• You’re confident navigating regulated and evidence-driven markets.
• You know how to move between strategic planning and operational detail.
• You care deeply about building access to care—not just revenue.

Nice-to-haves

• Experience in women’s health, digital therapeutics, or neurotechnology.
• Familiarity with CMS, private payer negotiations, or employer-sponsored health strategies.
• A track record of working cross-functionally in early-stage teams.
• Comfort presenting to boards, investors, or external partners.
• Passion for closing equity gaps in healthcare access.
• A data-informed mindset and fluency with forecasting tools and commercial analytics.

Why Join Samphire?

• We're redefining how women manage their health through noninvasive neurotechnology.
• Join at a defining moment and help translate scientific breakthroughs into scalable, equitable access to care.
• You’ll own a key part of our company’s long-term success—building the business model that allows us to grow with purpose.
• You’ll collaborate with a mission-first, high-trust team.
• We’re a remote-first company with presence in London, San Francisco, New York, and Boston. We offer fully equipped office space in Central London.

How to apply

Send your application with subject line 'VP of Commercial Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV/resume/Linkedin
• Context on relevant past experiences and why you would be a good fit for Samphire.

Our selection process includes strategy and culture interviews with team members. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.

As Head of Product at Samphire, you’ll be foundational in shaping the experience, accessibility, and impact of the world’s first brain stimulation therapy designed for women’s chronic pain. You’ll own our product strategy end-to-end—from device UX and mobile app features to technical workflow and long-term user engagement.

Reporting to the CEO and working closely with engineering, design, clinical, and commercial leaders, you’ll define the roadmap that helps our patients thrive—and ensures our product is as groundbreaking in delivery as it is in science.

This is a hands-on leadership role for someone who can zoom between strategy and detail, and who wants to build a product category from the ground up. You’ll lead the charge in transforming a powerful neurotechnology into a trusted, human-centered product experience.

What You’ll Do

Product Strategy

Define and own the product roadmap across device, app, and supporting systems. Prioritize features that drive clinical outcomes, improve usability, and support commercial goals.

Patient Experience

Design seamless, empathetic user experiences for people living with PMDD, endometriosis, and chronic pelvic pain. Build tools that help patients feel supported, empowered, and engaged.

Clinical Integration

Work with clinical, regulatory, and scientific teams to ensure the product supports evidence-based care. Shape how clinical protocols are translated into product workflows, content, and reporting.

Hardware-Software Coordination

Bridge our hardware and software teams to ensure end-to-end coherence—from electrode placement to in-app guidance, compliance tracking, and outcome measurement.

Go-to-Market Enablement

Support the commercial team in designing product experiences that work across DTC, provider, and payer channels. Define how onboarding, reporting, and engagement differ by user type.

Data-Driven Insights

Collaborate with data science to identify signals from usage, adherence, and outcomes. Use these insights to refine protocols, guide personalization, and inform future product lines.

Cross-functional Leadership

Act as the connective tissue across product, design, engineering, clinical, and business. Ensure product decisions are grounded in both user empathy and scientific integrity.

Team Building

Recruit, mentor, and lead a high-performing product team over time. Establish product processes that are lightweight, scalable, and designed for impact.

What We’re Looking For

• 7+ years of experience in product leadership, ideally in healthtech, medtech, or consumer hardware/software.
• You’ve owned roadmaps that span physical products and digital platforms.
• You’ve launched products in regulated environments and worked cross-functionally with clinical, regulatory, and engineering stakeholders.
• You think deeply about product-market fit and how to build trust through experience design.
• You care deeply about user outcomes—and you build with empathy, clarity, and conviction.
• You know how to navigate ambiguity and bring people with you.

Nice-to-haves

• Experience in neurotechnology, digital therapeutics, women’s health, or chronic care.
• Familiarity with user journeys in a healthcare setting, mobile health tools, or connected devices.
• A background in behavioral design, patient adherence, or health equity.
• Experience building for both B2C and B2B2C channels.
• Technical fluency in app/hardware integration and health data ecosystems.
• Strong storytelling skills and experience presenting to boards, investors, or partners.

Why Join Samphire?

• We're redefining how women manage their health with neurotechnology—starting with tDCS for PMDD and endometriosis.
• Join us at a pivotal moment, and help build a product experience that delivers dignity, relief, and scientific precision.
• You’ll have end-to-end ownership in shaping a category-defining healthtech product.
• We’re a remote-first team with presence in London, San Francisco, New York, and Boston. We offer fully equipped office space in Central London.

How to apply

Send your application with subject line 'Head of Product Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV/resume
• Links to past projects/contributions.
  

Our selection process includes technical and culture interviews with team members. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.

As Data Science & AI Lead at Samphire, you’ll be foundational in building the intelligence layer behind the future of women’s neurohealth. You’ll develop the models, algorithms, and tools that transform research and commercial data into personalized care—empowering patients and clinicians with deeper insight, smarter feedback, and better outcomes.

You’ll join our small, science-led team at a crucial phase: we’re moving from trial data collection to real-world intelligence. Reporting to the CEO and working closely with our product, clinical, and engineering teams, you’ll shape how we use data to drive everything—from adaptive stimulation protocols to predictive outcomes models.

This is a role for someone who wants to build from first principles. You’ll lay the foundation for data science at Samphire, architecting systems that combine neuroscience, real-world data, and AI to enable the next generation of patient-centered neurotechnology.

What You’ll Do

Data Strategy and Infrastructure

Design and own the data science roadmap for Samphire. Define how we collect, structure, and use data across clinical studies, patient usage, and device signals.

Model Development

Develop machine learning models to personalize treatment, predict outcomes, and optimize adherence. Build algorithms that interpret neurophysiological signals, patient-reported outcomes, and app/device interactions.

Scientific and Clinical Integration

Work with our neuroscience, clinical, and regulatory teams to ensure models are evidence-based, interpretable, and ready for use in regulated environments. Support biomarker discovery and exploratory data analyses from clinical trials.

AI Productization

Collaborate with product and engineering to bring ML models into production—whether in-device, in-app, or in backend platforms. Translate insights into features that improve patient outcomes and product performance.

Cross-functional Leadership

Partner with clinical operations, hardware, and commercial teams to ensure data efforts align with company goals. Contribute to trial design, user research, and patient engagement through data-informed decisions.

Security and Compliance

Ensure our data practices meet the highest standards of privacy, security, and ethical use—especially in sensitive areas like mental health and women’s health.

Team Building

As needed, recruit and lead a small, high-caliber team of data scientists and ML engineers as the company grows. Foster a culture of scientific rigor, technical excellence, and mission-driven problem-solving.

What We’re Looking For

• 3+ years of experience in data science, machine learning, or AI—ideally in healthtech, neurotech, or digital therapeutics.
• You’ve built and deployed predictive models in production environments, and you understand the nuance of working with real-world health data.
• You’re fluent in statistical modeling, signal processing, and supervised and unsupervised ML.
• You’ve led end-to-end projects that connect raw data to product decisions or clinical outcomes.
• You thrive in cross-functional environments and know how to communicate technical insight to diverse audiences.
• You care about building tools that serve real people—not just optimizing metrics.

Nice-to-haves

• Familiarity with mobile and wearable data.
• Experience working with neurophysiological signals (e.g., EEG, HRV, behavioral patterns).
• Experience collaborating on regulated software products (e.g., SaMD).
• Fluency in Python, cloud data pipelines, and MLOps best practices.
• Strong publication record or open-source contributions.

Why Join Samphire?

• We're redefining how women manage their health—starting with tDCS for PMDD and endometriosis.
• Join at a defining moment and build the intelligence systems that turn raw signals into real care.
• You’ll have full ownership of data strategy, with the resources and autonomy to experiment, scale, and shape what personalized neurocare can be.
• We’re a remote-first company with presence in London, San Francisco, New York, and Boston. We offer fully equipped office space in Central London.

How to apply

Send your application with subject line 'Head of Data Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV/resume
• Links to any relevant projects/contributions

Our selection process includes technical and culture interviews with team members. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.

As a Brand Designer at Samphire, you’ll be foundational in shaping how the world sees the future of women’s brain health. You’ll design experiences that make our neurotechnology not just accessible—but empowering, beautiful, and trusted by patients, clinicians, and researchers alike.

You’ll join our small, mission-driven team during an exciting period of growth. Reporting to our Creative Director, you’ll collaborate closely with our teams across product, clinical, content, and marketing to craft thoughtful and cohesive brand experiences across all channels—from our website and clinical trial materials to digital campaigns and patient touchpoints.

This is a multidisciplinary design role suited for someone who thrives in early-stage environments and wants to help define the design language of a category-defining brand.

What You’ll Do

Brand Design

Design compelling, emotionally intelligent visuals across Samphire’s marketing, product, and brand moments—including website, campaigns, packaging, and events.

Campaign Creative

Help create and execute campaigns that elevate awareness and trust in our brand—from our clinical trials for PMDD and endometriosis to broader educational and community initiatives in women’s neurohealth.

Design Systems

Develop and maintain Samphire’s visual identity and brand guidelines. Build design systems and libraries that scale across mediums—typography, colors, iconography, UI components, and more.

Marketing Design

Design digital assets, one-pagers, sales decks, and conference materials that are not only beautiful but also highly functional across DTC, HCP, and partner audiences.

Visual Storytelling

Collaborate on photo, video, and motion content to help communicate the science and personal impact of Samphire’s work. You’ll help humanize complex neurotech through clear, empathetic design.

Cross-Functional Collaboration

Partner with our product, marketing, research, and ops teams to ensure design is an integrated force across the company—not an afterthought. Be a creative bridge between strategy and execution.

What We’re Looking For

• 4+ years of experience in brand, marketing, or visual design—at an agency, tech company, or health brand.
• Strong portfolio that demonstrates an eye for detail, systems thinking, and the ability to tell compelling stories through design.
• Fluency in Figma, Adobe Creative Suite, and other design tools.
• Strong design fundamentals: typography, color theory, layout, and hierarchy.
• Experience building and scaling design systems.
• Ability to maintain a high bar for craft and elevate the work of others
• Comfort working autonomously and collaboratively in a fast-moving, ambiguous environment.

Nice-to-haves

• Experience in healthcare, wellness, or science-focused brands.
• Familiarity with motion design or video editing.
• A systems-level thinker who’s as excited to build the brand foundation as they are to iterate and evolve it.
• Passion for women’s health, neuroscience, or closing gaps in medical equity.
• Curiosity and kindness—you lead with empathy, humility, and a builder’s mindset.

Why Join Samphire?

• We're redefining how women manage chronic pain through noninvasive neurotechnology—starting with tDCS for PMDD and endometriosis.
• Join at a defining moment and help build our brand from the ground up.
• You’ll help translate groundbreaking clinical research into human-centered design.
• You’ll have autonomy to lead, experiment, and directly shape how we show up in the world.
• We’re a remote-first team with presence in London, San Francisco, New York and Boston. We offer fully equipped office space in Central London.

How to apply

Send your application with subject line 'Brand Designer Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV, resume or LinkedIn profile.
• Links to your portfolio.

Our selection process includes several technical and culture interviews with team members. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.

Samphire is seeking a Regulatory Affairs Lead to spearhead our regulatory strategy and execution across the U.S., Europe, and future global markets. This is a pivotal role for a clinical-stage neurotechnology company aiming to transform the care status quo for women. You’ll lead our work navigating 510(k), De Novo, and EU MDR pathways, shaping the regulatory infrastructure that will enable our at-home brain stimulation therapies to reach patients worldwide.

This is a highly cross-functional and high-impact position: you'll collaborate closely with our clinical, product, and executive teams to chart and de-risk our path to market for PMDD, endometriosis, and future indications.

What You’ll Do

Regulatory Strategy

• Design and own Samphire’s global regulatory roadmap across current and future markets.
• 510(k) or De Novo submissions in the U.S. and MDR submissions in the EU., as well as ongoing compliance with our ISO13485, ISO9001 and other practices.
• Identify optimal regulatory classification and pathways for pipeline indications and new product features.

Submission & Documentation

• Prepare, submit, and manage regulatory filings, including pre-submissions, technical files, and labeling reviews.
• Coordinate responses to regulatory agency inquiries and inspection readiness efforts.
• Work with internal teams to ensure all technical and clinical documentation meets regulatory standards.

Global Market Readiness

• Drive country-specific market entry plans, including potential partnerships with international regulatory consultants.
• Stay on top of evolving requirements in key regions and maintain regulatory intelligence databases.

Cross-functional Collaboration

• Partner with clinical, product, and quality teams to align development plans with regulatory requirements from the start.
• Participate in study design, risk management, and device testing strategies that support regulatory approval.
• Work with legal and external advisors to manage IP, labeling, and promotional material reviews.

What We’re Looking For

• 2-10 or more years of experience in medical device regulatory affairs.
• Deep expertise in FDA regulatory processes, including 510(k), De Novo submissions, and 21 CFR Part 820 quality system requirements.
• Experience navigating EU MDR requirements and preparing or reviewing CE marking/compliance documentation.
• Proven track record of leading regulatory submissions from pre-submission to clearance or approval.
• Excellent technical writing skills and the ability to author regulatory documentation.
• Strong cross-functional collaboration skills and experience working with clinical, engineering, and legal teams.
• A bachelor’s degree in a scientific, engineering, or regulatory-related field is required. RAC certification or an advanced degree is considered a plus.

Nice-to-haves

• Experience working with neuromodulation devices, wearable medical technology, or digital therapeutics.
• Background in women’s health or pain-related medical devices.
• Familiarity with regulatory frameworks outside the U.S. and EU, such as in Canada, Australia, or Asia-Pacific regions.
• Prior experience managing or preparing for FDA or notified body audits.
• You should feel comfortable navigating ambiguity in a fast-paced, early-stage startup environment.

Why Join Samphire?

• Help bring science-backed, patient-centered neurotechnology to millions of women —starting with PMDD and endometriosis.
• Be the architect of our global regulatory strategy and a driver of Samphire’s clinical and commercial success.
• Join at a pivotal moment with autonomy to shape process, strategy, and culture.
• Work flexibly.

How to apply

Send your application with subject line 'Regulatory Affairs Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV, resume or LinkedIn profile.
• Motivation to join Samphire.

Our selection process includes several technical and culture interviews with team members. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.

Samphire Neuroscience is a London-based women’s lifestyle neurotechnology company, developing medical grade hardware and software solutions for women’s health needs with a mission to change the lives of historically underserved communities by delivering evidence-based solutions.

We are seeking a Clinical Research Associate to join our growing team. We welcome and encourage applicants from diverse backgrounds.

About you

• Clinical Research Expertise: You have 1–5 years of experience (or a PhD) in clinical research, preferably within neurotechnology, women’s health, or related medical fields.
• ⁠⁠⁠Mission-Driven: You’re deeply committed to advancing women’s health and are excited by the prospect of pioneering neurotechnology-based solutions.
• Problem Solver: You have a track record of identifying challenges in research and implementing effective resolutions.
• Autonomous & Organised: You thrive in environments where you can manage priorities with minimal oversight, and you excel at transparent, efficient communication.
• Leadership & Collaboration: You’re comfortable leading clinical projects and engaging with external stakeholders (CROs, ethics boards, academic advisors).
• Hands-On Approach: You enjoy both the big-picture aspects (trial design, strategy, regulatory milestones) and the day-to-day tasks (data analysis, participant recruitment).
• Flexible & Adaptable: You value asynchronous work styles, self-scheduling, and are ready to pivot quickly as new insights or opportunities arise.

About the role

• Plan & Execute Clinical Trials: Oversee study design, participant recruitment, ethics approvals, and data management—particularly focusing on pivotal U.S.-based investigations.
• Coordinate Across Teams: Collaborate with product, legal, and leadership teams to integrate clinical findings into hardware and software solutions while maintaining compliance and safety standards.
• Develop Thought Leadership: Work with scientific advisors and external partners to publish peer-reviewed studies, thought leadership pieces, and popular health articles on women’s health, neurotechnology, and well-being.
• Contribute to Product Strategy: Use clinical insights to inform feature development, user experience, and potential new product lines or services.

What we offer

Samphire has multiple years of runway and puts effort in assembling the core team for long-term leadership in our space. We offer:

• ⁠⁠Competitive salary based on experience.
• ⁠⁠⁠Equity options.
• Office space in central London. Hybrid schedule possible.
• UK-standard holiday policy, pension contributions in the UK (unless opted out), NHS and other employment-based benefits, other well-being and learning benefits offered by Samphire.

How to apply

Send your application with subject line 'Clinical Affairs Application - Last Name, First Name' to Em at em@samphireneuro.com with:

• Your CV or LinkedIn profile.
• Links to any relevant work or projects you've been a part of.
• A brief note on why you are passionate about working in the realm of women's health.

Our selection process includes several technical and culture interviews with team members. We highly prioritise inclusivity and respect for all candidates. Should you need any adjustments to our standard hiring process, please mention it in your application.