A brain-based way to live for women

When it comes to women's health, the brain is the missing link.

Medically certified Non-invasive Non-hormonal

Hormones send messages. The brain is where they are received.

It all starts in the brain.

Mood shifts, motivation changes, energy dips - it's easy to blame your hormones. But most women, with or without symptoms, have similar hormone levels. What you're feeling is your brain's response to them.

It’s not random. It’s a rhythm.

Your cycle follows a smart, natural pattern. When you understand how the brain responds at each phase, it becomes something you can work with - not something you just get through.

Science-led tools for real-life support.

We use neuroscience, clinical technology and thoughtful design to create tools that help you feel clearer, steadier and more in control - from brain fog, pain and mood to burn out and beyond.

The only menstrual health platform that takes a brain-first approach to cycle wellness.

Learn more

Keep track in your own words

Discover patterns in your experiences

Integrate your data and your care plan

Bring loved ones on the journey

The world’s first hormone-free, drug-free and non-invasive treatment for menstrual pain and mood symptoms.

Discover Nettle™

Users report better focus and energy - even on period days at work or the gym.

67% saw reduced low mood symptoms in one month - with no severe side effects ever reported.

72% feel real relief after just one month's use - no drugs, no hormones.

With specialized support for those who need it.

Too often, systems treat symptoms in isolation. We work across the brain, body and cycle - connecting the dots between pain, mood, focus, hormones and more.

Discover our brain-based perspectives on women’s health conditions below.

Endometriosis

Highly prevalent chronic inflammation.

Premenstrual syndrome

Widespread but often overlooked mood and body shifts.

ADHD and neurodiversity

Everyday differences in focus and attention.

Neuroplasticity

The brain's ability to reorganize and adapt through experience.

Premenstrual dysphoric disorder (PMDD)

Frequently misdiagnosed severe hormonal sensitivities.

Dysmenorrhea

Cramping and pain before or during menstruation.

Both Samphire and Nettle™ have been built from the ground up on the latest science in women’s health.

In collaboration with leading organizations, our research teams are working to ask and answer pressing questions, closing the research gap that has impacted women’s health for too long.

Backed by science, proven by you.

Our solutions are informed by neuroscience, and designed specifically for menstrual health. These are the experiences of people using them every day. Read all reviews

Nettle has genuinely changed my life. I have just finished my fourth cycle of trying it and my symptoms were reduced to about 10%. It felt like very mild PMS compared to the severe, life threatening PMDD I usually suffer with.

Jessica

Incredible - Nettle has helped me immensely and the customer service is also brilliant. I have PMDD and ADHD which I don’t medicate for and I was surprised/delighted that it significantly reduced the symptoms of both of these conditions.

Hope

I've actually found my pain levels have reduced since using this device!

Alison

The changes have been remarkable. My mood and motivation have improved significantly, and I’ve experienced zero menstrual pain! It’s been a total game-changer!

Steph

I have suffered from unbearable pain during my periods and experienced very strong PMS symptoms. I was shocked to learn that it was indeed PMS (and endometriosis..). Abdominal pain on the first day of my period is still there, but milder—I only need one painkiller instead of three, which is already an improvement.

Silvija

Nettle has been life-changing for me. It has significantly improved my mental health, not just during the intense phases of PMDD before my period. But I actually feel much better during the rest of my cycle, too.

Jasmin