Pharmacologic (drug) solutions include painkillers, antidepressants, anxiety medication, GnRH agonists, etc. Hormonal solutions include the pill, hormonal IUDs (like the Mirena coil) and hormonal implants. Holistic solutions include supplements (such as magnesium, vitamin B6, omega-3, zinc, vitex agnus and tumeric), dietary changes (like the anti-inflammatory diet or caffeine/alcohol avoidance), herbal remedies, castor oil packs, physical therapy, exercise and movement changes.