You know these symptoms. We help you change them.
Nettle™ supports your brain in handling symptoms - with no hormonal interference.
- Low mood, emotional crashes or irritability (PMS, PMDD)
- Fatigue and brain fog (endometriosis, PMS)
- Cramping and pain sensitivity (dysmenorrhea (period pain), endometriosis)
- Cycle-related mood spirals (PMDD)
Frequently Asked Questions
See our full FAQ list here.
Your brain naturally runs on electricity, and neurons, the main cells in the brain, communicate using electrical signals called action potentials. Nettle™ uses the natural language of neurons to help rearrange and regenerate neural pathways - a process known as neuroplasticity.
This is done by administering safe and small electrical pulses to brain regions where these fluctuations occur. We are able to target them via the placement of the electrodes on the headband, one targeting your dorsolateral prefrontal cortex (DLPFC) and the other targeting your insula via your motor cortex (M1). During your luteal phase, fluctuations occur in these specific brain regions which contribute to symptoms of PMS and menstrual pain such as low mood, anxiety, brain fog and cramps.
This stimulation gets neurons firing in a way that is more consistent with follicular phase activity, empowering you to feel your best even during the premenstrual phase. The technology Nettle™ employs is well-known and validated from the fields of depression and chronic pain treatment, and is known as transcranial direct current stimulation (tDCS).
No, Nettle™ does not have any direct impact on the hormone levels in your body and will not affect your menstrual cycle. The physical and psychological symptoms that Nettle™ is designed to address all manifest as brain activity in the dorsolateral prefrontal cortex and motor cortex.
There are important contraindications that apply to using Nettle™. If any of the below contraindications apply to you, you should not use Nettle™.
- Persons who are under 18 years old.
- Persons with a history of seizures or epilepsy.
- Persons who are pregnant or may be pregnant. Note: if you are trying to conceive, or conceive accidentally, Nettle™ will not interfere with your hormones or chances, and there are no known side effects of women using the technology underlying Nettle™ in the first trimester.
- Persons experiencing active suicidal thoughts.
- Persons with a pre-existing neurological condition.
- Persons with a lesion, tumour or other defect in your skull, cranium or brain.
- Persons with an implant inside their skull, cochlear implant or implanted hearing aid.
- Persons with implanted medical devices, such as a cardiac pacemaker or neurostimulation devices, such as spinal cord stimulators, vagal nerve stimulators, auricular stimulators, or deep-brain stimulating electrodes. Note: external/non-invasive stimulators will not interfere with Nettle™'s efficacy or safety, but it is recommended not to use them at the exact same time.
If you are unsure about whether any contraindications apply to you, you must consult with your physician before continuing, especially if you are under the care of a physician for any conditions related to the central nervous system (e.g. neurology).
How Nettle™ works, and why it's so gentle.
Nettle™ uses transcranial direct current stimulation (tDCS) — a clinically validated, non-invasive method that stimulates the areas of your brain responsible for mood, focus, and pain regulation.
- You don’t feel a buzz or jolt, but sometimes a tingly, itchy feeling for the first 5 minutes as your skin adjusts.
- You simply feel more like yourself — clearer, calmer, steadier.
- Users report the benefits increasing over time with regular use, see for yourself here.
Science-backed, with not a single severe side effect.
- No medication or hormones.
- No sedation, fatigue, or rebound symptoms.
- Medical certification (class IIa) and clinical studies in PMS and Dysmenorrhea with trials underway for PMDD & endometriosis
- Over 1,000 tDCS trials worldwide since 1990
- Built for easy daily use at home
- Mild side effects include itching and tingling
Guiding your Nettle™ setup
Place the grey electrode covers into the electrode cases within the band and soak the electrode covers in saline solution until they feel spongey and wet. It may take more liquid than you think depending on the thickness of your hair.
Place Nettle™ comfortably on your head and press it onto your scalp. Your hair and shoulders near the headband will get a little wet - we recommend styling your hair post session.
Connect with the Samphire App and start your 20-minute session. You're free to do other things in the meantime, just keep your headband in place for good contact.
Join the users who describe their experience as "life changing."
Read more user feedback here.
Relief without compromise - and with financial support.
Everyone deserves effective, brain-based care. That's why our payment options are as flexible and supportive as Nettle™ itself.
90-day risk free trial
Try Nettle™ for three full cycles. If you don't experience meaningful relief, return it within 90 days for a full refund — no questions asked. This policy reflects our confidence in Nettle™'s effectiveness and our commitment to your satisfaction.
Paypal and Klarna
We've partnered with Klarna and Paypal for flexible payments. Choose to split your payment into manageable installments, making it easier to invest in your well-being without upfront financial pressure.
Workplace benefits
You may be eligible for financial support with workplace benefit programs through Zest, Juniper, and Heka. If you don't know whether your insurance provider covers Nettle™, reach out to them directly to inquire.