"What if there was a drug-free and effective way to manage both menstrual pain and mood disorders?"
Drug and hormone free relief for period pain & mood
Science meets self-care. Cutting edge neurotechnology combined with ancient, time-tested practices for daily relief.
Balance
starts in the brain
Our award-winning solutions are designed to boost and balance your brain health across the cycle. It’s menstrual care that starts where your cycle really begins.
All natural, drug and hormone-free
Clinically tested, studied and validated
Holistic pairing of modern and ancient techniques
Smart cycle predictions to help you plan ahead
Feel better from home - just 20 minutes a day, a few days each cycle.
Why the brain
Neuroplasticity holds the key
Your brain is the connection between your hormones and how you feel. We use both active and passive strategies to balance brain activity across your cycle - leading to fewer up and downs, and more stable, sustainable menstrual cycles.
How hormones affect your brain across your cycle
We study PMS, PMDD, endometriosis, focus, mood and more
Personalized support through integrated wearables and software
Evidence
94% of our users feel better in just three months.*
“I waited for my bleak day... the one I usually spend holding back tears... It didn’t come.”
“Samphire Neuroscience is redefining women’s health with brain-based wearables”
* Based on our clinically validated, double-blind study on Nettle™ (WIND 2024)
What we help with
Explore our perspectives on women’s health below.
Too often, systems treat symptoms in isolation. Samphire’s solutions work across the brain, body and cycle - connecting the dots between pain, mood, focus, hormones and more.
Endometriosis
Highly prevalent chronic inflammation.
Premenstrual Syndrome
Widespread but often overlooked mood and body shifts.
ADHD and Neurodiversity
Differences in focus and attention.
Neuroplasticity
The brain's ability to reorganize and adapt through experience.
Premenstrual Dysphoric Disorder
Severe PMS symptoms causing mood changes and physical discomfort.
Dysmenorrhea
Painful menstrual cramps that can disrupt daily activities.
Sleep and Rest
Supporting quality sleep to restore energy and balance.
Emotions and Mood Swings
Managing sudden mood shifts and emotional sensitivity.
Stress and Anxiety
Reducing tension and calming the mind during the cycle.
Feel better
every day of every cycle.
Nettle
United KingdomEuropean Union+47 countries
Discover Nettle™ 
Clinically proven to relieve menstrual pain and low mood
Class lla medical device, approved in UK and Europe
Feel better from home - just 20 minutes a day, a few days each cycle.
Samphire
Global availability
$6.99 / month
$69.99 / year
Personalized symptom tracking and insights across your cycle
Breathwork and meditation tailored to your cycle phase
Smart cycle predictions to help you plan ahead
Lutea™
United StatesCanada
Buy from $589.00
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Maximize wellbeing throughout the cycle, based on Nettle™'s technology
FCC registered and 60601 tested wellness device
Feel better from home - just 20 minutes a day, a few days each cycle.
Backed by science, proven by you.
These are the experiences of people using our solutions every day.
I'm four cycles in... and will never look back. The changes were gradual and cumulative, but by the third cycle I felt as though my life had completely changed, I haven't had to take a day off work due to PMDD symptoms since the second cycle of using Nettle.
Emma
I really love this company. It is weird to say I feel seen and cared for by them. I just don't think I have felt like this with any other business.
Rachel
Has been life-changing for me. It has significantly improved my mental health, not just during the intense phases of PMDD before my period. But I actually feel much better during the rest of my cycle, too.
Jasmin
Then in the third month, my PMS symptoms were reduced by 80%! I still have menstrual pain, but the intensity has decreased again a bit.
Moko
Blog
Our latest research
Our science and technology teams write extensively on why the brain matters in women’s health.
